CT-guided biopsy for musculoskeletal lesions.

The study of musculoskeletal tumors greatly improved with the use of computed tomography (CT) and magnetic resonance imaging (MRI). These studies offer excellent imaging of a lesion’s anatomical extension and a clear identification of its active part after contrast administration. However, modern imaging is essentially morphologic; its low specificity only allows for etiological diagnosis in a few patients.1,2 Therefore, biopsy should remain the last step of staging for definite diagnosis and treatment planning for patients with musculoskeletal tumors.